Summary
Sam and Dean Winchester relied heavily on their arsenal of weapons to hunt and save lives in Supernatural. Without these weapons, they wouldn't have been as successful.
The demon-slaying weapon introduced in season 3 revolutionized demon extermination, providing a more efficient means of eliminating these supernatural beings. Regrettably, it also had the unintended consequence of causing harm to the individuals inhabited by the demons, resulting in collateral damage.
Although Sam and Dean had the ability to take further action to rescue the human hosts of the demons, they began placing a higher importance on eliminating the demons themselves, ultimately casting them in a negative light within the Supernatural realm.
Sam and Dean Winchester possessed an array of weapons to combat supernatural creatures in the TV show Supernatural. Surprisingly, one particular weapon ended up turning them into adversaries. Dean carried a trunk filled with a variety of armaments such as machetes for vampire slaying, silver blades for dispatching shapeshifters, their trusty handguns, and The Colt, a weapon capable of eliminating almost anything. In a twist, Dean even attempted to use throwing stars in the dramatic series finale, only to be thwarted by Sam.
These weapons played a vital role in Sam and Dean's mission of "hunting things, saving people, the family business." Their job would have been impossible without this arsenal. Countless lives were rescued thanks to the extensive collection of weaponry stored in Dean's trunk. Regrettably, their efforts to save the world resulted in some unintended casualties. Among their armament, one particular weapon proved immensely beneficial, albeit not in the manner they originally intended.
Supernatural's Demon-Killing Blade Killed The Human Hosts Too
The introduction of Ruby wielding the demon-killing blade during Supernatural season 3 revolutionized the game. This powerful weapon provided a much simpler method to eliminate demons, as there was no longer a need to trap them; they could be swiftly dispatched. However, a significant drawback emerged from this newfound efficiency. While killing the demon also resulted in the death of the possessed human, there was still a chance to save the host by performing an exorcism, provided they hadn't succumbed entirely to their demonic possession. In such cases, Dean and Sam would rush the afflicted individual to the hospital for urgent medical care. Although the blade's implementation brought about a reduction in casualties, it also meant that fewer lives could be saved in the process.
Were Sam & Dean REALLY Killing Humans During Supernatural
Unfortunately, Supernatural saw numerous casualties among humans, many of whom fell victim to possession. Dean was responsible for eliminating many members of the evil Styne family as well as a few of the British Men of Letters. Surprisingly, Dean's kill count surpasses that of Sam's when it comes to fellow humans. At times, Dean displayed a ruthless demeanor that set him apart. Although Sam's use of demon blood to expel demons was controversial, he made a valid point about the blade's lethal nature compared to his method which actually saved lives.
Regrettably, Sam and Dean could have taken additional measures to ensure the survival of those affected by their demons. Bobby, for instance, managed to survive after stabbing himself with the knife, but only because the brothers promptly rushed him to the hospital. Bobby, although paralyzed, lived through the ordeal. Regrettably, they did not make similar efforts for their other victims. Despite the knife facilitating their elimination of demons, this approach contradicts the very essence of their family's mission, ultimately painting Sam and Dean as the antagonists in Supernatural.
Some of the victims may have been beyond saving. Numerous demons they expelled from their hosts nearly caused their deaths. Earlier seasons always left them devastated when this occurred. Regrettably, in later seasons, they grew less concerned about the fate of the host once the demon had departed or been eradicated. It would have been preferable if Supernatural had continued to depict Sam and Dean's efforts to rescue the possessed individuals.