Spider-Man 2: Complete Guide to Villains and Boss Battles

Spider-Man 2: Complete Guide to Villains and Boss Battles

Prepare to face an extraordinary line-up of adversaries in Spider-Man 2 Gear up to battle a formidable array of villains as you dive into this thrilling game

Marvel's Spider-Man 2 is an expansive game, showcasing epic battles that rank among the franchise's finest. Throughout the game, players must face a multitude of enemies in their quest to conquer the story. These adversaries are encountered at various stages and demand specific strategies to triumph over.

What sets these foes apart is their possession of distinctive powers, rendering them formidable adversaries. To overcome these challenges, players must unlock new abilities and enhance their suits, equipping themselves with the necessary tools to combat and triumph over these formidable opponents. A total of eight villains await players in their thrilling journey through Marvel's Spider-Man 2.

All Villains In Spider-Man 2

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Most of the adversaries in Spider-Man 2 will make their appearance in Main Missions, while only a few will be encountered during side missions. In order to provide a convenient reference, the following table features a comprehensive list of all the villains that players will engage with in Spider-Man 2.

Villain

Location

Villain Voice Actor

Sandman

  • Players will fight Sandman during the Surface Tension main mission. As depicted in the video above, this fight against Sandman is a great example of some of the boss fights players will encounter later.
  • Leandro Cano

Lizard

  • Due to Kraven's interference, Dr. Connors turns into Lizard again. Players will fight him in the It Chose You mission.
  • Mark Whitten

Mr. Negative

  • Mr. Negative is freed by Kraven, which bothers Miles a lot. This particular villain can be encountered during the No Escape main quest.
  • Stephen Oyoung

Kraven

  • Kraven, the greatest hunter in the world, turns his attention toward the home of Miles and Peter. In his quest to hunt strong opponents, Kraven not only hunters supervillains but also the two heroes. Players will fight in Anything Can Be Broken and Don't Be Scared missions.
  • Jim Pirri

Scream

  • Things take a turn for the worse when Mary Jane turns into something very dangerous. Players will have to rescue her in This Isn't You main mission.
  • Laura Bailey

Venom

  • Venom was a key attraction for Spider-Man 2. Players will fight this villain in Set Things Right and Together missions.
  • Tony Todd

Wraith

  • Wraith will be an ally early on in the game, but players will have to defeat her as the story progresses. She appears as a villain in the I Knew You Had It In You mission.
  • Tara Platt

Mysterio

  • The master of illusions will try his luck at fighting the heroes once again. It is up to the players to stop him. They will fight him in the Grand Finale.
  • Noshir Dalal

Players will also have to fight Peter in one of the missions, but it would be an exaggeration to call him a villain.

Spider-Man 2 is now available on PlayStation 5.