Summary
Grey's Anatomy is known for its unique medical cases, some of which are based on real-life occurrences, adding to the suspense and captivation of the show.
The incorporation of authentic medical cases provides the writers with the opportunity to craft gripping narratives and delve into the boundaries of the doctors' talents and treatments.
The series has addressed a range of health conditions, albeit occasionally portraying exaggerated and inaccurate portrayals of them.
Grey's Anatomy is renowned for its compelling portrayal of the personal lives of doctors, as well as its intriguing medical cases, some of which are drawn from real-life events. The show follows a group of highly skilled doctors as they navigate the challenges of their surgical careers, complex hospital politics, and unprecedented medical situations. With 19 seasons and counting, the show has managed to create numerous captivating storylines, leaving viewers in awe of the writers' imagination.
Throughout its long run, Grey's Anatomy has undergone significant changes, but one aspect has remained constant since season 1: the inclusion of fascinating medical cases that keep audiences on the edge of their seats, eagerly awaiting the outcome for each patient. This beloved and award-winning medical drama on ABC often presents fictionalized cases that are carefully crafted to captivate viewers and deliver thrilling episodes. However, some of the most compelling stories have been inspired by real-life incidents. It is important to note that while these storylines were fictional and often exaggerated, they were influenced by actual events. Here are nine Grey's Anatomy storylines that drew inspiration from real-life situations.
9 A Little Girl Who Could Not Feel Any Pain
Grey's Anatomy, season 3, episode 3, "Sometimes a Fantasy," centers around a young girl who believes she possesses extraordinary abilities due to her inability to experience pain. Ultimately, she receives a diagnosis of congenital insensitivity to pain with anhidrosis, or CIPA. Zoanne Clack, an executive producer for the show, confirmed in an Entertainment Weekly interview that the storyline stemmed from a real medical case discussed in a published article. Intrigued by this condition, the writers of the show sought to explore the limits of the doctors' pain management techniques for this young girl and the various ways she could potentially injure herself, eventually weaving it into a compelling narrative.
8 Richard Webber's Cobalt Poisoning
In the latest episode of Grey's Anatomy, season 16, episode 21 titled "Put On A Happy Face," an unexpected change in Richard Webber's behavior hinted at the possibility of him suffering from Alzheimer's disease. However, both Meredith and DeLuca questioned this diagnosis and decided to conduct a blood test, which ultimately revealed that Webber was actually dealing with cobalt poisoning as a result of a previous hip replacement surgery. Cobalt poisoning, although uncommon, is a real condition that can affect individuals who have undergone hip replacements. Showrunner, Krista Vernoff, explained to Deadline that this diagnosis allowed the writers to explore a range of symptoms for Webber without permanently incapacitating his character.
7 April's Baby Having Osteogenesis Imperfecta
6 The Santa Claus With Cyclic Vomiting Syndrome
Season 11, episode 11 of the show introduced one of the most heart-wrenching storylines. Titled "All I Could Do Was Cry," this episode depicted April's journey as she discovered that her unborn baby had osteogenesis imperfecta, a genetic bone disorder that makes bones prone to fractures. In an interview with The Hollywood Reporter, actress Sarah Drew, who portrays April, revealed that this poignant storyline was inspired by the real-life experience of a close family friend. Drew felt compelled to bring this personal tale to the attention of the show's creator, Shonda Rhimes, after learning about April's pregnancy. Together, they decided to incorporate the narrative of Drew's friend into the show.
In "Second Opinion," the sixth episode of Grey's Anatomy's ninth season, a homeless Santa Claus enters the hospital and raises suspicion of drug-seeking behavior. However, it is later revealed that he suffers from cyclic vomiting syndrome, a condition characterized by sudden and recurring episodes of nausea and vomiting. This storyline was inspired by Chandra Wilson, the actress who portrays Miranda Bailey, and her personal experience with her own daughter who also battles this syndrome. Wilson shared with People that her daughter endured severe vomiting and excruciating abdominal pain, which proved to be a challenging diagnosis for medical professionals.
5 Meredith's Mini Livers
One of the most fascinating and groundbreaking endeavors undertaken by Meredith in Grey's Anatomy was her pioneering work in producing "mini-livers" through the use of lymph nodes. Subsequently, it was revealed that this ground-breaking innovation drew inspiration from a distinguished faculty member at the McGowan Institute for Regenerative Medicine, located at the University of Pittsburgh. Dr. Eric Lagasses, the faculty member in question, had been dedicating his efforts towards the creation of an ectopic liver within the lymph node.
4 Miranda Bailey’s 12-Person Domino Transplant Surgery
In the Grey's Anatomy's fifth season, episode 5 titled "There's No I in Team," Dr. Bailey takes charge of a team comprising surgical residents and interns. Together, they undertake a groundbreaking procedure known as a "domino surgery." This involves performing 12 kidney transplants simultaneously in six separate operating rooms. Although this medical marvel had not been attempted prior to the episode's airing, it soon became a reality. Just a year later, in 2009, the renowned John Hopkins hospital successfully orchestrated the world's first-ever "domino donor" kidney transplant. Spanning multiple medical centers and states, six pairs of donors and recipients were involved in this monumental medical achievement.
3 Meredith’s New Alzheimer's Theory
2 A Man Who Grew Tree-Like Warts
: In the latest season of Grey's Anatomy, a significant development in Meredith's career journey unfolds as she embarks on a controversial research endeavor focused on Alzheimer's. Challenging the prevailing belief within the medical community, Meredith posits a hypothesis that sets her apart – she questions the association between the disease and the amyloid plaque in the brain. Back in 2006, a renowned neuroscientist named Sylvain Lesné spearheaded groundbreaking research on the formation of sticky plaques in the brain, primarily caused by the amyloid beta protein, which was thought to be linked to autism. However, recent revelations cast doubt on the validity of Lesné's findings, raising suspicions that they may have been fabricated.
In Grey's Anatomy season 7, episode 3, titled "Superfreak," a patient is afflicted by untreated HPV, resulting in the growth of tree-like warts. Clack, in an Entertainment Weekly interview, confirmed that this storyline was inspired by a real case involving a young boy who experienced similar warts. The writers incorporated this narrative after extensively researching the boy's situation and consulting with experts. The true incident occurred in a secluded village, which explains the character's reclusive lifestyle and lack of treatment.
1 A Woman Who Has Spontaneous Orgasms
In the Grey's Anatomy episode titled "Yesterday" from season 2, Izzie encounters a patient who experiences spontaneous and uncontrollable orgasms. This condition, known as Persistent Sexual Arousal Syndrome, is not a fictional creation by the show's writers but a genuine medical phenomenon. According to Clack's statement to Entertainment Weekly, the writers based this storyline on a case they came across in a journal article. They had attempted to incorporate it into previous episodes, but it felt more appropriate for "Yesterday," as it allowed for the development of a romantic connection between Izzie and Alex. Sources: Various.