Comprehensive Guide to the Voice Cast of Big Mouth

Summary

Big Mouth is a hilarious and relatable animated series that explores the wild and messy world of puberty through the eyes of middle schoolers.

The show's diverse and inclusive cast challenges expectations and fearlessly explores taboo subjects, establishing its position as one of the most inclusive shows on television. The voice cast is comprised of highly skilled actors, including Nick Kroll, John Mulaney, Jenny Slate, Maya Rudolph, and many others, who brilliantly give life to the characters with their comedic talent.

As the penultimate season of Big Mouth returns to Netflix, both new viewers and long-time fans may be curious about the latest members of the voice cast and characters. Created by Nick Kroll, Adam Goldberg, Mark Levin, and Jennifer Flackett, this popular animated series revolves around a group of middle schoolers and explores the highs and lows of growing up. With a mix of horror, excitement, and shock, the preteens navigate through awkward and raunchy situations, all while maintaining relatability and humor.

What sets Big Mouth apart is its surrealistic approach to depicting the chaotic and messy teenage mind during puberty. Starting with its early episodes, the show focuses on best friends Nick Birch (voiced by Kroll) and Andrew Glouberman (voiced by John Mulaney) as they navigate their first sexual experiences and other typical pubescent milestones. Along the way, they are accompanied by their hormone monsters, who represent their brooding and often poorly timed sexual desires. While season 8 of Big Mouth will mark the series' final chapter, it will continue to inspire future raunchy coming-of-age comedies.

Big Mouth's Main Characters

Nick Kroll As Nick Birch & Maurice The Hormone Monster

Despite the show's ensemble approach, certain characters in Big Mouth play a more pivotal role in the series' narrative.

Nick Kroll, who is the co-creator of Big Mouth, voices the lead character Nick in the show. Nick, who is also known for his roles in The League and Kroll Show, has showcased his voice acting skills in movies like Sausage Party and Sing. In Big Mouth, Kroll takes on various roles including Nick, Maurice the Hormone Monster, and Coach Steve.

John Mulaney As Andrew Glouberman

Nick’s Jewish best friend, Andrew, faces continuous harassment from Maurice. Andrew is voiced by John Mulaney, a former Saturday Night Live writer and stand-up comedian. In addition to portraying Andrew, Mulaney also lends his voice to characters like Babe the Blue Ox, Detective Florez, Grandpa Andrew, and Mint. Mulaney is widely recognized for his roles in popular productions such as Spider-Man: Into the Spider-Verse, Documentary Now!, and The Bear.

Jessi Klein As Jessi Glaser

Jessi, the intelligent and spirited leading female character in Big Mouth, grapples with body insecurities. Renowned comedian Jessi Klein lends her voice to this dynamic role. Klein, known for her stellar contributions to Comedy Central, notably gained recognition for her work on Inside Amy Schumer.

Jenny Slate (Seasons 1–4) & Ayo Edebiri (Season 4–Present) As Missy Foreman-Greenwald

Jason Mantzoukas as Jay Bilzerian

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Stand-up comedian Jenny Slate gained fame by creating Marcel the Shell with Shoes On, an internet sensation that eventually turned into a feature film. Apart from this, she also lent her voice to the character of Missy for the first four seasons of the popular show Big Mouth. However, following criticism for voicing a Black character, she decided to step down from the role. Starting from season 4, Ayo Edebiri, known for starring in The Bear, took over the role of Missy. Edebiri's talent extends beyond acting and includes writing, with credits in both TV and film such as Dickinson, Bottoms, and Theater Camp.

Jay Bilzerian, a bisexual teenager, wrestles with his desires and necessities. Portrayed by the versatile Jason Mantzoukas, known for his roles in numerous acclaimed comedy series such as Brooklyn Nine-Nine, The League, and The Good Place. Additionally, Mantzoukas graces the silver screen as part of the cast for John Wick: Chapter 3—Parabellum.

Fred Armisen as Elliot Birch

Although Nick’s father Elliot is kind and well-intentioned, Fred Armisen, best known for his work on Saturday Night Live and Portlandia, is the perfect fit for portraying him. Armisen frequently appears in guest spots, ranging from Los Espookys to Broad City, adding his unique touch to the role.

Maya Rudolph as Connie the Hormone Monstress

Connie the Hormone Monstress appears in Big Mouth whenever significant events occur in the lives of the show's young female characters. The role is voiced by Maya Rudolph, a former member of SNL's cast and a prominent figure in the critically acclaimed film Bridesmaids, which received an Oscar nomination. In addition to portraying Connie, Rudolph also lends her voice to other characters on Big Mouth such as Diane Birch, the Ghost of Elizabeth Taylor, and the Ghost of Whitney Houston.

Jordan Peele as the Ghost of Duke Ellington

Simply known as “Duke,” this Big Mouth character is trapped between heaven and hell, and remains at his location of death: Nick’s home. After gaining widespread recognition through his sketch series Key & Peele, the actor-turned-filmmaker solidified his position as the go-to director in the horror genre with acclaimed films such as Get Out, Us, and Nope.

Big Mouth's Supporting Cast

A strong ensemble cast relies heavily on its supporting characters, as they have the power to enhance a series beyond its main characters and expand its scope. Big Mouth is a prime example of this, boasting a plethora of remarkable supporting characters. This is partly due to the exceptional voice cast, consisting of renowned actors, comedians, and other notable personalities. Among the standout supporting players in the series are:

Andrew Rannells as Matthew MacDell.

Paula Pell as Barbara Glouberman — Andrew's mother.

Richard Kind as Marty Glouberman — Andrew's overbearing father.

Seth Morris as Greg Glaser — Jessi Glaser's always-stoned father.

Jessica Chaffin as Shannon Glaser, Jessi's mother.

June Diane Raphael as the popular student Devin LeSeven.

Jak Knight as popular student DeVon Furtive-Oldman.

Gina Rodriguez as Gina Alvarez, a member of the soccer team who goes through puberty early on.

Neil Casey portrays the characters of Lars, a student, as well as Detective Dumont.

Joe Wengert takes on the role of Caleb Linden, a student who may be on the autism spectrum, Stan the Hormone Monster, and several other recurring characters in Big Mouth.

Fran Gilesspie as the student Samira.

Jon Daly as Judd Birch, Nick's dark-yet-caring older brother.

Leah Birch is portrayed by Kat Dennings in seasons 1–4, while Chloe Fineman takes on the role from season 5 onwards.

Monica Foreman-Greenwald, Missy's mother, is played by Chelsea Peretti. She also voices the sentient cell phone named Cellsea.

Heather Lawless as Jenna "Jay's Mom" Bilzerian.

Mark Duplass as Val Bilzerian — Jay's bully of an older brother.

Paul Scheer as Kurt Bilzerian, another of Jay's bullying older brothers.

Nathan Fillion as himself (a.k.a. Missy's celebrity crush).

Rob Huebel as a teacher, Mr. Terry Lizer.

David Thewlis as Lionel St. Swithens — a Shame Wizard and the Hormone Monsters' mortal enemy who haunts the kids, stoking their deepest shame.

John Gemberling as Tyler Pico, Nick's immature hormone monster.

Gil Ozeri as Wiggles, Missy's stuffed toy; Brad the couch cushion; and Gil, a Hormone Monster.

Kristen Bell as Pam, a pillow Jay has a sexual relationship with.

Jack McBrayer & Craig Robinson as Nick's pubic hairs.

Rosa Salazar as seventh-grade teacher Miss Benitez.

Michaela Watkins as Dina Reznick — the Cantor of the Temple Beth Amphetamine.

Zach Woods as the student Daniel and also a sock.

Natasha Lyonne as Suzette, a motel pillow.

Alia Shawkat as Roland, a friend of Nick's from New York.

Kristen Wiig as Jessi's vulva.

Andy Daly as Dr. Wendy Engle — Nick's doctor.

Harvey Fierstein as Jerome, an older gay man.

Jean Smart stars as Kitty Bouchet, an anthropomorphic purple cat working in the Depression Ward of the Department of Puberty.

Bobby Cannavale portrays Gavin Reeves, a powerful and passionate Hormone Monster.

Zachary Quinto as Aiden, Matthew's ex-boyfriend.

Ali Wong as new student Ali.

Julie Klausner as Cherry Marashina, Andrew's cousin.

Judd Hirsch as Lewis Glouberman, Andrew's late grandfather.

David Cross as Skip Glouberman, Marty's brother and Andrew's uncle.

Thandiwe Newton as Mona, Missy's British accented hormone monstress.

Maria Bamford as Tito Taylor Thomas the Anxiety Mosquito.

John Oliver as Harry, a camp counselor.

Seth Rogen as Seth Goldberg, a Canadian camper.

Somali Rose as Missy's overalls.

Zach Galifianakis as the Gratitoad, a talking toad that expresses gratitude.

Josie Totah as camper Natalie el-Khoury.

Lena Waithe as Missy's cousin Lena.

Quinta Brunson as Missy's cousin Quinta.

Sterling K. Brown as Michael Angelo, Jessi's ex-boyfriend from New York.

Brandon Kyle Goodman as Walter Las Palmas, Nick's Lovebug turned hate-worm.

Keke Palmer as Rochelle Hillhurst, Missy's lovebug who was a hate-worm.

Pamela Adlon as Sonya Poinsetta, Jessi's lovebug.

Kristen Schaal as Bernadette "Bernie" Sanders.

Jemaine Clement as Simon Sex, a sensitive, shroom-taking Hormone Monster.

Brian Tyree Henry as Missy's crush Elijah.

Chris O'Dowd as Flanny O'Lympic, Andrew's Irish accented lovebug that debuted in Human Resources.

Peter Capaldi as Seamus MacGregor, Nick's long-lost Scottish grandfather.

Cole Escola as Montel, Maury's and Connie's biological non-binary child.

Megan Thee Stallion as Megan — a Hormone Monstress modeled after the rapper.

Zazie Beetz as Dani, Megan's client.

Stephanie Beatriz as high school student Lulu.

Patrick Page as Dread, the evolution of Tito.

Big Mouth's Guest Stars

Big Mouth features an outstanding main and supporting cast, along with numerous noteworthy guest stars. These guest appearances, although brief, highlight the immense popularity of the coming-of-age comedy among both viewers and actors. In addition to Lin-Manuel Miranda and other notable contributors in season 7, the series also showcases a remarkable lineup of A-listers, including Jess Harnell as Dwayne Johnson, a fictionalized portrayal of the wrestler-turned-actor.

Mae Whitman as Tallulah Levine, a friend of Leah's who crushes on Nick.

Jon Hamm as a plate of Scallops.

Martin Short as Gordie, the main character of the Canadian Netflix hit, Gordie's Journey.

Carol Kane as the Menopause Banshee, a banshee that represents female menopause.

Wanda Sykes as the ghost of Harriet Tubman.

Rob Riggle as Col. Adderall, the personification of the ADHD medication.

Antoni Porowski, Tan France, Karamo Brown, Bobby Berk, and Jonathan Van Ness from Queer Eye as themselves.

Retta as Daisy Ellington, Duke Ellington's mother.

Paul Giamatti portrays Andrew's excrement, while Maya Erskine and Anna Konkle portray Misha and Izzy, respectively. These characters are seventh-graders who Nick and Andrew have a romantic encounter with, cleverly referencing the actors' hit show PEN15.

Aidy Bryant as Emmy Fairfax, a Lovebug.

Kumail Nanjiani as himself.

Adam Scott as teacher Dylan Keating.

Hugh Jackman as a fictitious version of himself.

Annaleigh Ashford as The Rice Purity Test, an anthropomorphic quiz.

Amber Ruffin as Amber, Elijah's aunt.

Ira Glass as himself.

Jeff Goldblum as the Apple Brooch.

Steve-O as himself.

Tyler The Creator as Jesus.

Juliet Mills as Rita St. Swithens, the Grand Dame of Humiliation and Lionel's mother.

Adam Levine, Ed Helms, and Matt Rogers as members of the boy band, Bros 4 Life.

Lupita Nyong’o as Asha, a Kenyan Shame Wizard.

Padma Lakshmi as Priya, Marissa's mother.

Maitreyi Ramakrishnan as a student named Marissa.

Billy Porter as Ocean, a high school student.

Rosie Perez as Petra the Ambition Gremlin.

Randall Park as Peter "Pete" Doheny, a Logic Rock that represents logic within humans.

Lin-Manuel Miranda as a singing pubic hair.

Don Cheadle as himself.

Editor's P/S

As a Gen Z fan, I have a few thoughts on the voice cast of Big Mouth. First, I think it's great that the show has such a diverse and inclusive cast. It's important to have shows that represent different voices and experiences, and Big Mouth does a great job of that.

Second, I think the voice cast is incredibly talented. The actors all bring their own unique energy to the characters, and they really make the show come to life. I especially love Nick Kroll's performance as Nick Birch. He perfectly captures the awkwardness and insecurity of being a teenager.

Overall, I think the voice cast of Big Mouth is one of the best things about the show. They bring the characters to life and make the show relatable and funny. I can't wait to see what they do in the final season.